NYSCF in the News

NYSCF once again had a large presence at the thirteenth annual meeting of the International Society for Stem Cell Research (ISSCR) in Stockholm, Sweden. NYSCF Scientist Dr. Mitsutoshi Yamada was invited to give a talk on his research using nuclear transfer for the prevention of mitochondrial diseases; a key topic after the UK Parliament voted to approve starting clinical trials using these techniques for the prevention of disease this spring.

Each year, the ISSCR annual meeting travels to a different location around the globe bringing together top researchers and organizations for the intensive, four-day event, this year held at the Stockholmsmassan Exhibition and Congress Centre. Next June, the fourteenth annual meeting will be held in San Francisco, California. 


Read more about the 13th Annual ISSCR Meeting >>

NYSCF Principal Investigator Dr. Danny Freytes led a team of NYSCF scientists at the NYSCF Research Institute in a study investigating the inflammatory response of the immune system after cardiac injury. The scientists tested the protein cross-talk between stem cell-derived heart cells and macrophages - a type of immune cell - in a simulated inflammatory environment in the laboratory to shed light into how these interactions can be harnessed to design successful therapies. 

Understanding the cardiac inflammatory response after injury, and how stem cell-derived cardiac cells behave in this environment, is a key component of developing successful cell replacement treatments or cardiac patch therapies for damaged or sick cardiac tissues. 


Read the paper in the Journal of Tissue Engineering and Regenerative Medicine >>

NYSCF - Robertson Neuroscience Investigator Dr. Takaki Komiyama, University of California San Diego, identified a key step in how neurons process motor learning. Using two-photon imaging in awake mice, the scientists showed that somatostatin inhibition within a specific class of neurons is a key regulator of learning-related changes and the acquisition of motor skills. 

Understanding how normal neural circuits work in motor skills learning has vast implications on research and ultimately finding treatments and cures for diseases and injuries related to these neural pathways.


Read the paper in Nature Neuroscience >>

NYSCF - Robertson Stem Cell Investigator Dr. Jacob Hanna, Weizmann Institute of Science, tested an alternate method of stem cell transdifferentiation - the process of a somatic cell turning into other cell types without passing through a pluripotent state - showing that the vast majority of reprogrammed mouse heart and brain stem cells created using this method did, in fact, briefly pass through a pluripotent state.  

These findings, published in Nature Biotechnology, underscore the importance of understanding the steps and phases during cell reprogramming using different methods. 


Read the paper in Nature Biotechnology >>

NYSCF hosted the Sixth Annual Innovators Retreat bringing together over 50 NYSCF-supported scientists for a full week of presentations, introductions, and discussion on the latest research in the field. Talks during the week included a keynote address featuring Dr. Christopher White of Microsoft, formerly at DARPA, who spoke about software he developed to search the entire internet – including the dark web – to help stop human trafficking.

NYSCF Research Institute scientists, NYSCF – Druckenmiller Fellows, and NYSCF – Robertson Investigators comprise the global NYSCF Innovator community, the preeminent network of stem cell scientists doing cutting-edge research to bring us closer to cures.


Learn more about the NYSCF - Druckenmiller Fellows >>

Learn more about the NYSCF - Robertson Investigators >>

Susan L. Solomon presented at the Days of Molecular Medicine Conference at the Karolinska Institutet, the institution responsible for awarding the Nobel Prize for Physiology or Medicine, in Stockholm. The theme for this year focused on Emerging Partnerships in Translational Science and Medicine: Academia, Hospitals, Foundations and the Private Sector. Ms. Solomon spoke about “Getting to cures: A new model of high-tech collaborative research.”

In addition, Ms. Solomon hosted a panel about the future of regenerative medicine at the New York BIO 25th Anniversary Conference and served as a keynote interviewee in London at the World Stem Cells and Regenerative Medicine Congress. The interview, titled, Realising the promise: How the NYSCF is enabling the acceleration of cures through stem cell research, offered attendees a glimpse of NYSCF’s unique game-changing approach to modern medicine. 


Read about the Days of Molecular Medicine Conference >>

Read about the New York BIO Conference >>

Read about the World Stem Cells and Regenerative Medicine Congress>>

A team of NYSCF scientists demonstrated that small volumes of cryopreserved peripheral and cord blood can be reprogrammed efficiently in a convenient, cost-effective, and scalable way. Further, the scientists developed induced pluripotent stem (iPS) cell colonies 2-3 weeks faster than previous reports. The iPS cells derived were also transgene-free, meaning they did not have genomic rearrangements.

This method, published in Stem Cell Reviews and Reports, enables the reprogramming potential and, therefore, potential for use in research and future treaments of innumerable limited biobanked blood samples, including those from children and newborns that cannot easily provide larger blood samples. 


Read the paper in Stem Cell Reviews and Reports >>



NYSCF scientists presented the NYSCF Global Stem Cell Array technology and NYSCF’s approach to accelerating research at two leading meetings.
The talks included a symposium entitled Japan-USA: Regenerating the World of Medicine hosted by the American Chemical Society in New York City as well as a panel on commercialization and sustainable business models in biotech at the Global Technology Community Stem Cell Summit in Boston.


Read more about the Japan-USA Symposium >>

Read more about the GTC Stem Cell Summit >>

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