NYSCF – Robertson Investigator Changes Leukemia Cells Into Harmless Immune Cells

NYSCF – Robertson Stem Cell Investigator Dr. Ravindra Majeti, Stanford University School of Medicine, and a team of researchers showed that cancerous, immature white blood cells from patients with precursor B acute lymphoblastic leukemia can be reprogrammed into harmless macrophage cells.

The researchers showed that these reprogrammed cells were no longer able to cause disease in immunodeficient mice and that this reprogramming may already occur to some degree in patients with this type of leukemia. This research, published in the Proceedings of the National Academy of Sciences, indicates that reprogramming leukemia cells into macrophages may represent a previously unidentified therapeutic strategy for this disease.

 

Read the press release in Medical Xpress >>

Read the paper in the Proceedings of the National Academy of Science >>

Diseases & Conditions:

Cancer and Blood

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