NYSCF – Robertson Investigator Unlocks Clues to Cell Pluripotentcy
NYSCF – Robertson Stem Cell Investigator Dr. Jacob Hanna, of the Weitzmann Institute of Science in Israel, and his team discovered a critical role played by the modification of a signal molecule in vivo in naive and primed stem cells. In addition, the scientists identified regulatory modules that influence both naive and primed stem cell pluripotentcy in an opposing manner.
This study, published in Science, will help researchers understand why and how stem cells transition through states of differentiation through their different molecular properties. This type of research will lead to a better understanding of stem cell pluripotency and, ultimately, clinical use.