Hormone Prevents Stem Cell Death Following Lethal Radiation Dose
Radiation exposure often triggers cell death in hematopoetic, or blood-forming, stem cells. A study in Nature Medicine shows that the addition of a hormone following exposure could...
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Cell Therapy Treats Gastrointestinal Disorder in Mice
A team led by Heather Young and John Furness has demonstrated a possible cell therapy to treat gastrointestinal motility disorders like Hirschsprung disease. For patients with...
Tuberculosis, a “Wolf-in-Stem-Cell-Clothing”
Under the cover of a mesenchymal stem cell, the tuberculosis (TB) bacterium persists, even years after living asymptomatically. A new study in Science Translational Medicine provides...
Scientists Create First “Disease in a Dish Model” of Rare Heart Condition
Arrhythmogenic right ventricular dysplasia/cadiomyopathy is a rare, inherited, and currently untreatable condition, which is a common cause of sudden death in adolescents. Researchers led by Daniel...
Researchers Develop Test to Pinpoint Transition in Degenerative Eye Disease
Approximately 20% of patients diagnosed with dry age-related macular degeneration develop the wet form, which leads to irreversible eye damage and eventual blindness. While the dry...
Allogenic Stem Cells Help Rats Recover from Stroke
Rats, immediately following an induced ischemic stroke, fared better when injected with allogenic mesenchymal stem cells than a placebo. While there was no evidence of stem...
Japanese Researchers Derive Kidney Tissue from Stem Cells
Japanese researchers led by Kenji Osafune report the successful generation of mesoderm kidney tissue from induced pluripotent stem cells. This particular tissue type—between a stem and...
New Research From NYSCF Investigator Could Treat ALS
Paola Arlotta, a NYSCF – Robertson Stem Cell Investigator, has reported in Nature Cell Biology the possibility to reprogram one type of neuron into another in...
NYSCF Neuroscience Investigator Featured in the Wall Street Journal
NYSCF Investigator Ed Boyden’s pioneering work in the field of optogenetics is profiled in the Wall Street Journal. By genetically engineering mice, Boyden and his colleagues...
NYSCF Breakthrough Named to “10 Predictions That Will Transform Healthcare”
Genetic Engineering & Biotechnology News has named a recent breakthrough from the NYSCF Laboratory to its list of "10 Predictions That Will Transform Healthcare." This list captures...
Researchers Target Metabolism of Leukemia Stem Cells
Often, leukemia lays dormant before re-emerging. Researchers believe that a resistive subpopulation of leukemia stem cells underlie our current difficulty in eradicating this blood cancer....
Leprosy Bacteria Reprogram Schwann Cells into Stem Cells
It’s not just humans who can reprogram cells. The leprosy bacterium can infect and thereafter revert adult Schwann cells into stem-like cells. The infection is spread...
Stem Cell Therapy Offers Hope to Spinal Muscular Atrophy Patients
Children born with spinal muscular atrophy (SMA) have a grim prognosis: most infants rarely see it to their second birthday. This debilitating, genetic disease has no...
Biomaterial Acts as Stem Cell Scaffold, Promotes Cartilage Repair in Patients
Reported in Science and Translational Medicine, a light-activated hydrogel helps to repair damaged cartilage by acting as a scaffold for stem cells. Jennifer Elisseeff and collaborators...
Damage Stalled, Stopped in Duchenne Muscular Dystrophy Mouse Model
Duchenne muscular dystrophy (DMD), a rare genetic disorder, leads to muscle death and the formation of scar tissue due to a mutant copy of the dystrophin...
Stem Cells to Treat Fractures in France
Project REBORNE will commence clinical trials to help repair fractured bone in France. Following successful pre-clinical work and approval by the French Medicinal Agency, autologous mesenchymal...
Drug Reverses Deafness in Mice
Hearing loss in mammals is thought irreversible: damage wrought to ear hair cells can lead to permanent deafness. A new study in Neuron from Albert Edge...
No Difference in Immune Response for Embryonic and Induced Pluripotent Stem Cells
The results of a Nature study may quell long-held concerns over the safety of transplanted induced pluripotent stem (iPS) cells. In a 2011 investigation, transplanted...
ALS Mice Benefit from Neural Stem Cell Transplant per Meta-analysis Study
A meta-analysis of 11 studies reveals that undifferentiated, mulitpotent neural stem cells (NSC) from mice or humans may slow the onset and mitigate the symptoms of...
NYSCF CEO Susan L. Solomon Featured at ARM Biotech Showcase
During the 2013 Biotech Showcase in San Francisco, NYSCF CEO Susan L. Solomon presented on NYSCF’s role in the future of stem cell research at the...
SCOTUS Will Not Hear Appeal in Sherley v. Sebelius
The Supreme Court refused to hear an appeal from the plaintiff’s of Sherley v. Sebelius. Significantly, this marks the end of a years-long legal battle to...
Oxford Researchers Reverse Blindness in Mice
University of Oxford researchers report strides to reverse blindness in the Proceedings of the National Academy of Sciences. The group, led by Robert MacLaren, transplanted light-sensitive...
Time – Scientists Discover New Technique to Prevent Certain Inherited Disorders
Passing on genetic mutations for disease is one of the greatest fears among parents-to-be, but a new technique may alleviate some of those worries. Mitochondrial disorders...
Cancer Gene Essential for Stem Cell Maintenance
BRCA1, a gene commonly known for its role in cancer, has been found to play an essential role in hair follicle cell maintenance. As reported in...
HER-2 Positive Cancer Stem Cells Contribute to HER-2 Negative Breast Cancer
A paradox that finally explains why certain breast cancers respond to treatment has been uncovered by Jian Jian Li and colleagues. For HER-2 negative breast cancers,...