How The Microscopic Residents in Your Gut Could Influence Cognitive Decline
The Context: Your intestines are home to trillions of microbes that help you take in nutrients and maintain a healthy gut, and they are also known...
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Sergiu Pasca Recognized For His Work to Understand the Developing Brain
NYSCF – Robertson Stem Cell Investigator Sergiu Pasca, MD, of Stanford University has dedicated himself to understanding the brain: how it develops, how it works, and...
Bat Brains Offer A Glimpse into How We Navigate Through the World
The Problem: Human spatial navigation abilities are incredibly complex, and can go awry in diseases like Alzheimer’s. We know that the brain has specialized ‘place cells’...
About-Face: From ‘Grandmother Neurons’ to New Forms of Facial Recognition
The Problem: For decades, scientists have grappled with the mystery of facial recognition: how our brains turn visual information into memories. At one time, many hypothesized...
Retracing How Our Brains Develop After Birth
The Problem: Brain organoids, 3D models of brain tissue created from stem cells, have recently become very useful for studying brain development and disease. While they...
Parents Lead the Push for Rare Disease Cures
A rare disease diagnosis for a loved one can be devastating. The majority of rare diseases are pediatric, meaning they affect children from birth or early...
Creating a Human Nerve Circuit in a Dish to Study Movement Disorders
The Context: Neuromuscular disorders such as ALS arise from degeneration of brain cells that send signals to the muscles, and there are no treatments that address...
How Octopuses Taste by Touch
The Context: Scientists have long known that octopuses are able to taste what they touch with their tentacles, but the way their tentacles sense taste has...
Tackling COVID, Promoting Health Equity, and Delivering on the Promise of Regenerative Medicine: Highlights of the 2020 NYSCF Conference
“My oldest son, Andrew, is a cancer survivor,” said Tony Coles, MD, PhD, CEO of Cerevel Therapeutics. “He was afflicted with non-Hodgkins lymphoma when he...
Showing Up for Science: Celebrities and Stem Cells Take Center Stage at the NYSCF Gala
Hosted by CNN’s Chief Medical Correspondent Sanjay Gupta, MD, this year’s New York Stem Cell Foundation Research Institute Gala & Science Fair went virtual for the...
For People with This Genetic Defect, Overly Chatty Neurons May Underlie Schizophrenia Risk
The Context: 1 in 3,000 people has a genetic defect called 22q11.2 deletion syndrome, or 22q11DS, putting them at a greater risk for developing schizophrenia. However,...
Why the Microbes in a Mother’s Gut Could Matter for a Developing Baby’s Brain
The Context: Scientists know that the microbes in a mother’s gut can affect brain function in offspring, usually in response to stress, infection, or other adverse...
NYSCF Announces 2020 Class of NYSCF – Robertson Investigators
Top row: Drs. Raffaella Di Micco, Samantha Morris, José Ordovás-Montañés. Bottom row: Drs. Jiami Guo, David Schneider, John Tuthill New York, NY (October 20, 2020) – The...
For Children With a Rare Neurological Disease, a First-Ever Treatment May be on the Horizon
The Context: Pelizaeus-Merzbacher disease (PMD) is a rare genetic disorder that affects myelin, the ‘cable insulation’ that helps neurons send signals, leading to severe muscle stiffness...
NYSCF Scientists Create the ‘Stars’ of the Brain and Capture Their Rogue Behavior in Disease
Read the press release here. You may not have heard of astrocytes before, but your body is full of them: they make up more than...
When Astrocytes Attack: Stem Cell Model Shows Possible Mechanism Behind Neurodegeneration
Human stem-cell-derived astrocytes can be triggered to become toxic to neurons, opening the door for new understanding and treatment of neurodegenerative diseases. Featured image credit: Christina...
Kay Tye Delivers TED Talk on the Underpinnings of Mental Illness
NYSCF – Robertson Neuroscience Investigator Alumna and Salk Institute Professor Kay Tye, PhD, recently delivered a TED Talk on her pioneering work to illuminate how circuits...
NYSCF Scientists Talk Space, Stem Cells, and their Pioneering Study of MS and PD
The International Space Station (ISS) houses more than astronauts: the football-field-sized spacecraft is also home to a large range of research projects carried out in the...
Roadmap of Brain Development Offers Insight into Autism and Schizophrenia
The Context: Studying brain development can be difficult since scientists cannot easily access developing brain tissue. Creating models of human brain development from stem cells allows...
CYTOVIA Therapeutics and the New York Stem Cell Foundation Research Institute Enter into a Partnership to Develop iPSC-Derived CAR NK Therapeutics
Research teams will use stem cell and gene editing technologies to advance NK cell-based therapies for cancer New York, New York (January 9, 2020) – The...
For a Family Affected by Rare Disease, Stem Cells are Providing New Hope
When Ariya Panwala was born, she was a happy, squirmy baby — but after a few months, her parents noticed she wasn’t advancing as expected. Her...
How ‘Remixing’ a Gene May Lead to Schizophrenia and other Neuropsychiatric Diseases
The Context: NRXN1 is a gene that is broadly implicated in neuropsychiatric disorders such as schizophrenia, autism spectrum disorder, and epilepsy; however, the ways in which...
From Casual to Compulsive: How Brain Circuitry Affects Alcohol Use
The Context: Alcohol use disorders affect roughly 15 million Americans, but why some people are more susceptible to compulsive drinking than others is not well understood....
Precision Medicine and the Power of Stem Cells: Highlights of the 2019 NYSCF Conference
In 2006, Shinya Yamanaka, MD, PhD, made a discovery that revolutionized biomedical research and earned him a Nobel Prize. His lab found that stem cells, the...
New Hope for a Rare and Deadly Neurological Disease
The Context: Pelizaeus – Merzbacher disease (PMD) is a rare neurological condition typically diagnosed in infancy which often becomes fatal by a patient’s teenage years. While...