NYSCF Global Stem Cell Array®

Automated iPSC reprogramming, genome editing, and differentiation services

  • Gold standard industrialized iPSC production
  • Eliminates all manual manipulation and technical variability
  • Yields highly reproducible panels of iPSCs and differentiated lines
  • Massively parallel processing of samples

 

Services

Deposit iPSCs
  • iPSC expansion and quality control services
  • Ability to deposit iPSC lines into the NYSCF Repository for global distribution
iPSC Generation
  • Automated, high-throughput reprogramming of blood and skin samples
  • Traceable processes and project management infrastructure
  • Certificate of Analysis provided for each line verifying rigorous quality control
iPSC Genome Editing
  • Automated CRISPR/Cas9 knockouts
  • SNV edits for production of isogenic line pairs
iPSC Differentiations
  • High-yield protocols for differentiating PSCs into various cell types, including neuronal, glial, pancreatic, cardiac, hepatic, retinal, cardiomyocytes, immune
  • Numerous protocols automated – ability to differentiate hundreds of lines in parallel
  • Automated generation of organoid models, including brain and pancreatic
Cell-based Assays
  • Immunofluorescence
  • Cell painting
  • High content imaging
  • Gene expression analysis
  • Electrophysiology
  • Other phenotypic and functional assays of interest in 2D or 3D cultures with ability to scale up