NYSCF Research Institute scientists in collaboration with researchers at the Icahn School of Medicine at Mount Sinai refined a...
Alzheimer’s Disease Research at NYSCF
Alzheimer’s Disease Stem Cell News
Below are select publications outlining recent advancements in Alzheimer’s Disease research from NYSCF Innovators.
CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2N141I neurons. (Acta Neuropathologica Communications)
In this study, NYSCF scientists in collaboration with researchers at the Icahn School of Medicine at Mount Sinai refined a technique to turn skin cells from patients with mild cognitive impairment into the brain cells that degenerate first in Alzheimer’s disease.
This study outlines how NYSCF scientists in collaboration with scientists at the Icahn School of Medicine at Mount Sinai successfully generated a stem cell model of familial Alzheimer’s disease and identified genes that contribute to its pathology and onset.
Generation of iPSC lines from archived non-cryoprotected biobanked dura mater. (Acta Neuropathologica Communications).
This paper details how NYSCF scientists were able to generate induced pluripotent stem cell lines from bio-banked tissue taken from Alzheimer’s patients.