Research Capabilities

Stem Cell Genome Engineering

• We use gene editing to correct or create mutations in cells, helping us develop disease models and understand disease mechanisms.
• We have adapted CRISPR/Cas9 procedures for automated use on the NYSCF Global Stem Cell Array®, allowing this technology to be used at a large scale.
• Our platforms allow us to complete genetic modifications on multiple lines simultaneously.

Watch a presentation by NYSCF – Robertson Investigator, Feng Zhang, PhD, who helped pioneer the revolutionary CRISPR gene editing tool.

Drug Discovery & Disease Modeling

• We create validated iPSC lines for multiple disease states and controls. These models allow researchers to compare disease phenotypes to control cells and elucidate the mechanisms behind disease.
• We develop 2-dimensional and 3-dimensional cell culture platforms that can be used for complex, multi-cell type cultures as well as in-vitro organ systems.
• Our systems also allow medium-throughput compound testing to aid in the drug discovery process. These systems can test discrete compound collections on multiple disease cell lines and controls as well as assist in live cell and end point assay readouts.

Clinical Research

• Please see our study flyer and contact the Clinical Research group to learn more about participating in our research.

Kindly note that NYSCF does not offer clinical trials, stem cell therapy, or medical advice. We are not currently accepting embryo donations.