Shivatra Noi Talchai, PhD
Principal Investigator at King Mongkut's University of Technology Thonburi, Thailand
PhD, Columbia University
Postdoctoral Training, Columbia University
Dr. Talchai discovered that she could induce cells of the gut to release insulin, a function that had been previously associated only with the pancreas. This finding gives hope for developing new treatments for diabetes. Previously, scientists tried to replace lost insulin-producing, beta-cells, cells with new pancreatic beta-cells in diabetic patients. The insulin-producing intestinal cells may be able to substitute for beta-cells, since they have sugar-sensing receptors and can release insulin in proper response to blood glucose levels. Dr. Talchai is continuing her work in generating human insulin-producing cells from gut stem cells as a form of treatment for diabetes. She completed her postdoctoral studies at Columbia in Dr. Domenico Accili’s lab.