NYSCF Innovator Improves Neuron Derivation from Stem Cells
Creating consistent groups of mature neurons from stem cells remains challenging in the lab. NYSCF – Robertson Stem Cell Investigator and NYSCF – Robertson Stem Cell Prize recipient Dr. Marius Wernig and his team from Stanford University developed a method to consistently derive GABAergic neurons directly from human stem cells with high levels of maturity. The scientists used lineage-specific transcription factor programming to achieve these remarkable results.
Published in Nature Methods, this work represents an important step towards enabling the study of diseases affecting these neurons and their signaling ability.