NYSCF Innovator Studies Stem Cell Behavior in Adult Tissues

In the human body, adult tissues replace lost cells via pools of stem cells. However, the mechanisms of this process are not fully understood. NYSCF – Robertson Stem Cell Investigator Dr. Valentina Greco, Yale University, shed light on this process by studying the lifetime of individual skin cells from the ears and paws of mice using specialized imaging techniques.

The research, published in Science, suggested that skin stem cells have equal potential to divide or directly differentiate, and that cell behavior is not coordinated between cellular generations. This research sheds light on how a tissue is maintained through stem cell behaviors, a key piece of future regenerative medicine therapies. NYSCF – Druckenmiller Fellow Alumnus Dr. Panteleimon Rompolas was first author on the paper.

Read the paper in Science