NYSCF – Robertson Investigator Shows Stem Cells Can Serve as Niches for Progeny Cells
NYSCF – Robertson Stem Cell Investigator Dr. Jayaraj Rajagopal, Massachusetts General Hospital, discovered that parent stem cells can serve as niches, or cell maintenance and regulatory environments, for their daughter cells. Published in Nature, this research describes how airway progenitor cells send a forward signal to their progeny cells, and further, shows this signal is necessary for progeny cell maintenance.
Understanding the full mechanisms behind stem cell differentiation and maintenance is key to using stem cells to fulfill the promise of regenerative medicine.
In addition, NYSCF Junior Leadership Council Board Member Brandon Law contributed research and was an author on the paper.