Dieter Egli, PhD
Associate Professor at Columbia University
2012 NYSCF – Robertson Stem Cell Investigator Alumnus
2008 NYSCF – Druckenmiller Fellow Alumnus
PhD, University of Zurich, Switzerland
Postdoctoral Training, Harvard University, The NYSCF Research Institute
Bio
Dr. Egli is an Assistant Professor at Columbia University. His research focuses on the generation of therapeutically relevant cells for diabetes. His work has relevance for the use of stem cells to study disease, screen for new drugs, and cell replacement therapy. His research creating patient-specific stem cells using the DNA of patients with type 1 diabetes, first published in Nature in October 2011, was named the #1 Medical Breakthrough of 2011 by TIME magazine, which also named him one of 2011’s People Who Mattered. He received a NYSCF – Druckenmiller Fellowship in 2008.
During his fellowship, Dr. Egli studied the mechanisms of somatic cell nuclear transfer (SCNT), a technique to create a viable embryo from an adult body cell and a human egg cell. The technique involves transferring the DNA from the body cell into the egg cell. Dr. Egli studied the influence of the cell division cycle on the SCNT and demonstrated the importance of specific cellular regulatory factors for this process to proceed. In his independent role, he has continued this research, especially as it an apply to the treatment and cure of diabetes. He completed his postdoctoral studies at Harvard University and NYSCF with Kevin Eggan, PhD.
External Links
Research Area
Mentioned In
- Climbing for Cures: Five NYSCF Champions Summit the Tallest Mountain in North America
- First Children in United Kingdom Born After Receiving Mitochondrial Replacement Therapy that NYSCF Helped Pioneer
- Why Do So Many Embryos Fail in IVF?
- Gene Editing in Human Embryos Could Lead to an Unexpected Hazard
- Parent-Specific Stem Cells Provide Insight into Human Development
- Four NYSCF Innovators Featured In Nature Article on Embryonic Stem Cell Research
- NYSCF Innovator Investigates Genomic Instability in Cell Reprogramming
- NYSCF Research May Lead to Improvements in Reproductive Technologies
- New Therapy Target Identified for Obesity Disorder
- NYSCF Calls For Faster FDA Review to Curb Stem Cell Tourism Citing Baby Born Using Mitochondrial Replacement Therapy
- NYSCF Research Advances Mitochondrial Replacement
- New Type of Stem Cells that Accelerate Discovery
- NYSCF Research Breakthrough Featured in NYTimes Magazine Cover Story
- First Disease-Specific Stem Cell Line by SCNT
- NYSCF Scientists Find Compound To Preserve Beta Cell Function in Diabetes Model
- NYSCF Researchers Develop Scientific Technique to Help Prevent Mitochondrial Disease
- TIME Magazine Names New York Stem Cell Foundation Research #1 Medical Breakthrough of 2011