Designing materials to direct stem-cell fate
Nature, Review Insight “Proper tissue function and regeneration rely on robust spatial and temporal control of biophysical and biochemical microenvironmental cues through mechanisms that remain poorly...
1336 Results
Systems-level dynamic analyses of fate change in murine embryonic stem cells
Nature, Letters “Molecular regulation of embryonic stem cell (ESC) fate involves a coordinated interaction between epigenetic, transcriptional, and translational mechanisms.”Read More »
Fresh hope for German stem-cell patent case
Nature, News “The German federal supreme court has referred a controversial and already lengthy patent dispute about human embryonic stem (hES) cells to the European Court...
Drug discovery: Predicting promiscuity
Nature, News & Views “Most drugs are intended to be selective for a single protein target, but will commonly bind to several other targets too. Some...
Embryonic stem cells may restore brains damaged by radiation
Los Angeles Times, Health “Scientists at UC Irvine and UC San Francisco have found a potential new use for human embryonic stem cells – helping cancer...
CIRM Awards Seek to Move Cell Therapies to the Clinic
Science, News of the Week “Five years after it launched, the California Institute for Regenerative Medicine (CIRM) last week awarded its first disease-oriented grants”Ó$230 million to...
Culturing Stem Cell Awareness
Cell Stem Cell “The bond between the general public and stem cell research has long been tinged with misgivings.”Read More »
Slowing Brain Disease with Gene Therapy
Science, This Week in Science “X-linked adrenoleukodystrophy (ALD), the hereditary brain demyelinating disorder that was featured in the movie “Lorenzo’s Oil,” is typically treated by transplantation...
Gene therapy deserves a fresh chance
Nature “Initial interest in gene therapy waned after the technology failed to live up to expectation. Progress made since has received little attention, but suggests that...
New ‘Schizophrenia Gene’ Prompts Researchers To Test Potential Drug Target
“Johns Hopkins scientists report having used a commercially available drug to successfully “rescue” animal brain cells that they had intentionally damaged by manipulating a newly discovered...
A chemical platform for improved induction of human iPSCs
Nature, Abstract “The slow kinetics and low efficiency of reprogramming methods to generate human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in...
Fetal Cells Again?
Science, News Focus “Despite past failures and growing skepticism about cell therapy in general, scientists once again plan to test fetal cell transplants on Parkinson's disease”...
Chemical Reset
Nature, Research Highlights “Adult cells can be turned into ‘pluripotent’ or embryonic-like stem cells with the insertion of four genes “Ó Sox2, Oct4, Klf4 and c-Myc.”...
From stem cells to functioning strip of heart muscle
Harvard Science “A team of Harvard Stem Cell Institute (HSCI) scientists at Massachusetts General Hospital (MGH) and collaborators at Harvard’s School of Engineering and Applied Sciences...
NYSCF-Druckenmiller Fellow Justin Ichida is Lead Author on Groundbreaking Study
NYSCF applauds NYSCF-Druckenmiller fellow Justin Ichida on his recently published work in Cell Stem Cell, bringing us closer to turning adult cells into patient-specific stem cells...
NYSCF-Druckenmiller Fellow Justin Ichida is Lead Author on Groundbreaking Study
NYSCF applauds NYSCF-Druckenmiller fellow Justin Ichida on his recently published work in Cell Stem Cell, bringing us closer to turning adult cells into patient-specific stem cells...
Genetics of complex diseases
Nature, Editor’s Summary “Genome-wide association studies have identified hundreds of genetic variants associated with complex human diseases, but most confer quite small increments of risk.” Read...
Scanning for links to autism
Nature, Editor’s Summary “Autism is a highly heritable neurodevelopmental disorder, and yet very few specific susceptibility genes have been identified to date.” Read More »
Generation of Induced Pluripotent Stem Cells from Human Cord Blood Using OCT4 and SOX2
Cell Stem Cell, Brief Report “Two independent groups demonstrate that human cord blood (CB) is a ready source of somatic cells that can be reprogrammed to...
Regeneration Next: Toward Heart Stem Cell Therapeutics
Cell Stem Cell, Review “Stem cell biology holds great promise for a new era of cell-based therapy, sparking considerable interest among scientists, clinicians, and their patients. ...
The first UK human-pig hybrid embryos given go ahead
The Daily Telegraph (London) The first license to create human-pig embryos has been issued to a team studying heart disease. Read more »
What Condition Could Stem Cells Help First?
Newsweek “The answer almost doesn’t matter, because stem-cell research has become the latest casualty of a plague sweeping biomedical science: advances in the lab aren’t reaching...
FDA green lights stem cell clinical trial for Lou Gehrig’s disease
“The Rockville, Maryland based company Neuralstem has received US Food and Drug Administration (FDA) permission to test its spinal cord stem cells in twelve patients with...
Wisconsin, Morgridge scientists excise vector, exotic genes from induced stem cells
University of Wisconsin, Press Release “A team of scientists from the Morgridge Institute for Research at the University of Wisconsin-Madison reports that it has created induced...
Oncogenic potential in prostate cells
Nature, Editor’s Summary “A rare luminal stem cell population, termed CARN cells, has been identified in the mouse prostate.”Read More » See related article: “A luminal...