Genetic Variants Synergize to Confer Schizophrenia Risk
The Context: Schizophrenia has a strong genetic component. Scientists have discovered many genetic variants that may play a role in its onset, but each individual variant...
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Meet LADL: A New Technology for Controlling DNA Folding
The Context: To fit inside the nucleus of our cells, our DNA crumples up, forming loops and making itself compact. When certain sequences of looped DNA...
CRISPR to the RESCUE: Gene Editing Technology Gets More Versatile
The Context: CRISPR is a powerful gene editing tool which traditionally works by locating and modifying stretches of DNA within the genome. However, this technique creates...
CRISPR Gets an Upgrade Thanks to “Jumping Genes”
The Context: CRISPR is a powerful, ‘word-processor’-like tool for editing DNA, but currently it is much easier to eliminate undesired sequences than it is to accurately...
Gene Editing: The Science, Ethics, and Promise of a Revolutionary Technology
Perhaps in the past few years, you’ve started to hear more about CRISPR gene editing— the revolutionary technique that allows us to precisely manipulate the DNA...
NYSCF Hosts Launch of Jamie Metzl’s New Book: “Hacking Darwin: Genetic Engineering and the Future of Humanity”
“After 3.8 billion years of evolving by Darwinian principles, we are turning a corner and taking more control over all biology, including our own,” explained Jamie...
NYSCF Inks Strategic Partnership with Ngene Therapeutics
Research teams will use stem cell and gene editing technologies to advance cell-based therapies for devastating diseases New York, New York (January 9, 2019) – The...
Why We Need Stem Cell Avatars: Susan Solomon Speaks at IGNITION Conference
“It takes 13 years—after you have sunk 4 billion dollars into a drug—to figure out whether or not it will succeed, and your chance of being...
Claims of First Gene-Edited Babies Spark Concerns
Reports this week that a researcher in China has created genetically modified children using the gene editing technology CRISPR have been met with widespread concern. Dr....
Translational Research Takes Center Stage at NYSCF Conference
“Medicine shouldn’t be one size fits all,” National Institutes of Health (NIH) Director Dr. Francis Collins told the audience of the NYSCF Conference last week. “Think...
NYSCF Announces 2018 Class of NYSCF – Robertson Investigators
NEW YORK, NY (October 23, 2018) – The New York Stem Cell Foundation (NYSCF) announced the 2018 class of NYSCF – Robertson Investigators, welcoming six of...
How Does a Glitch in Genome Folding Lead to Disease?
The sequence of bases (As, Cs, Gs, and Ts) that make up our DNA matters: it is what determines our genetic blueprint, which in turn determines...
Dr. Maria Lehtinen Elucidates the Genetics Behind Brain and Speech Development
In a new study published in Neuron, a team from Boston Children’s Hospital led by NYSCF – Robertson Neuroscience Investigator Maria Lehtinen, PhD, discovered that a...
How Can Stem Cells Help Us Understand Rare Disease?
In a new article from the patient advocacy and research nonprofit Jordan’s Guardian Angels, NYSCF speaks about its work creating induced pluripotent stem cells from patients with Jordan’s...
NYSCF Partners with ToolGen, nSAGE to Integrate Gene Editing and Stem Cell Technologies
New collaboration aims to develop better therapies New York, NY (August 1, 2018) – The New York Stem Cell Foundation (NYSCF) Research Institute today announced a...
Dr. Feng Zhang Receives Grant From G. Harold and Leila Y. Mathers Foundation
NYSCF – Robertson Investigator Feng Zhang, PhD, Core Member at the Broad Institute of MIT and Harvard and Professor of Brain and Cognitive Sciences and Biological Engineering at...
SPRITE: A New Technique For Mapping DNA In Our Nuclei
Researchers at the California Institute of Technology led by NYSCF – Robertson Investigator Mitchell Guttman, PhD, have developed a new tool called SPRITE to uncover how...
Four NYSCF Innovators Named 2018 Howard Hughes Medical Institute Investigators
This week, NYSCF – Robertson Investigators Feng Zhang, PhD (MIT), Ed Boyden, PhD (MIT), Gaby Maimon, PhD (The Rockefeller University), and Zachary Knight, PhD (University of...
NYSCF – Robertson Investigator Feng Zhang Launches “Beam Therapeutics”
NYSCF – Robertson Investigator Feng Zhang, PhD, Core Member at Broad Institute of MIT and Harvard, Professor at Massachusetts Institute of Technology, along with David Liu, PhD, Professor...
NYSCF – Robertson Investigator Elected To European Molecular Biology Organization
NYSCF – Robertson Stem Cell Investigator Alexander Meissner, PhD, of the Max Planck Institute for Molecular Genetics was one of 62 scientists recently inducted into the...
NYSCF – Robertson Investigator Feng Zhang Featured On 60 Minutes
NYSCF — Robertson Investigator and MIT professor Feng Zhang, PhD, was interviewed on CBS’s 60 Minutes about CRISPR, the gene editing technology he helped pioneer that...
NYSCF Investigator Looks To Animal Genomes To Learn More About Human Disease
Elephants don’t get cancer. Well, they do, but not nearly at the same rate as other mammals. In a way, this is odd because cancer is...
CRISPR Gets A New Skill: Diagnosing Disease
CRISPR is everywhere. There’s so much work being done with this revolutionary gene-editing tool that it warrants its own journal. And researchers are still finding new...
The Adventures of Pioneer Factors
The DNA in each of our cells is identical, but not every cell expresses it in the same way. Genes are expressed in different ways at...
Unraveling The Mystery Of Our Scrunched-Up DNA
A group of researchers at the University of Pennsylvania led by NYSCF — Robertson Investigator Jennifer Phillips-Cremins, PhD, have developed a tool to examine why the physical...