Understanding Brain Regeneration in Axolotls

Axolotls have the ability to regenerate multiple organs, including their brains, throughout the course of their lives. This makes them an ideal model to study brain regeneration, particularly whether neuronal diversity, intricate tissue architecture and neuron connectivity can be regenerated.

NYSCF – Robertson Stem Cell Investigator Dr. Paola Arlotta, Harvard University, demonstrated that diverse, electrophysiologically functional neurons can be regenerated in axolotls after mechanical injury in her latest paper published in Elife. Research on brain repair in regenerative species helps pave the way for the eventual development of successful cell replacement strategies and repairs in the central nervous system of people.

Read the paper in Elife