HER-2 Positive Cancer Stem Cells Contribute to HER-2 Negative Breast Cancer
A paradox that finally explains why certain breast cancers respond to treatment has been uncovered by Jian Jian Li and colleagues. For HER-2 negative breast cancers, often treatments crafted for HER-2 positive patients prove effective. A new study in Clinical Cancer Research reports that a radiotherapy-resistant group of HER-2 positive cancer stem cells are present in HER-2 negative breast cancers. These findings may help to elucidate treatments.