Gabsang Lee, PhD

Gabsang Lee, PhD

Professor at Johns Hopkins University School of Medicine​

2011 NYSCF – Robertson Stem Cell Investigator Alumnus

2009 NYSCF – Druckenmiller Fellow Alumnus

PhD, Seoul National University, South Korea

Postdoctoral Training, Memorial Sloan Kettering Cancer Center


Dr. Lee is a Professor at Johns Hopkins University School of Medicine, where he is studying stem cells created from the cells of patients with rare diseases like Familial Dysautonomia, Charcot-Marie-Tooth disease, and muscular dystrophy in order to investigate their pathology and develop new treatments and therapies. During his time as a NYSCF – Druckenmiller Fellow at MSKCC, he established a novel methodology for direct derivation and prospective isolation of neural crest cells derived from human pluripotent stem cells.

Dr. Lee aimed to use stem cells to model specific genetic diseases such as familial dysautonomia (FD), a rare and fatal disorder primarily affecting nerve cells. By creating stem cell models, he was able to pursue a systematic drug discovery effort to find potential therapeutic options. Using a sophisticated analytical approach, he screened 6,912 chemical compounds, composed of FDA-approved drugs and natural products, and identified 8 validated hits, which demonstrated the feasibility of performing drug screening on stem cell models. He is continuing to work on rare diseases in his independent position. He completed his postdoctoral studies at MSKCC in Dr. Lorenz Studer’s lab.